Jump to content

File:5tdi cathepsinK odanacatib.png

Page contents not supported in other languages.
This is a file from the Wikimedia Commons
From Wikipedia, the free encyclopedia

5tdi_cathepsinK_odanacatib.png (800 × 600 pixels, file size: 266 KB, MIME type: image/png)

Summary

Description

The X-ray crystallography structure of human cathepsin K in complex with the covalent inhibitor odanacatib, shown in light blue with covalently modified catalytic cysteine in green. Odanacatib was studied in clinical trials as a cathepsin K inhibitor for osteoporosis. Rendered with PyMol from PDB: 5TDI​.

Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib. Law, S., Andrault, P.M., Aguda, A.H., Nguyen, N.T., Kruglyak, N., Brayer, G.D., Bromme, D. (2017) Biochem J 474: 851-864

PubMed: 28049758

DOI: 10.1042/BCJ20160985
Date 27 Deecember 2021
Source Own work
Author Opabinia regalis

Licensing

I, the copyright holder of this work, hereby publish it under the following licenses:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
GNU head Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License.
You may select the license of your choice.

Captions

Add a one-line explanation of what this file represents

Items portrayed in this file

depicts

image/png

b80059c67da66e9d55289ce9999a117048d48545

272,235 byte

600 pixel

800 pixel

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current06:35, 28 December 2021Thumbnail for version as of 06:35, 28 December 2021800 × 600 (266 KB)Opabinia regalis{{Information |Description=The X-ray crystallography structure of human cathepsin K in complex with the covalent inhibitor odanacatib, shown in light blue with covalently modified catalytic cysteine in green. Odanacatib was studied in clinical trials as a cathepsin K inhibitor for osteoporosis. Rendered with PyMol from {{PDB|5TDI}}. Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib. Law, S., Andrault, P.M., Aguda, A.H., Nguyen, N.T., Kruglyak, N....

The following page uses this file:

Metadata