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2-nitroimidazole nitrohydrolase

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2-nitroimidazole nitrohydrolase
Identifiers
EC no.3.5.99.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

2-nitroimidazole nitrohydrolase (EC 3.5.99.9, NnhA, 2NI nitrohydrolase, 2NI denitrase) is an enzyme with systematic name 2-nitroimidazole nitrohydrolase.[1] This enzyme catalyses the following chemical reaction

2-nitroimidazole + H2O imidazol-2-one + nitrite

This enzyme is present in the soil bacterium Mycobacterium sp. JS330

References

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  1. ^ Qu Y, Spain JC (April 2011). "Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance". Environmental Microbiology. 13 (4): 1010–7. doi:10.1111/j.1462-2920.2010.02406.x. PMID 21244596.
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