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Bicyclogermacrene synthase

From Wikipedia, the free encyclopedia
Bicyclogermacrene synthase
Identifiers
EC no.4.2.3.100
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Bicyclogermacrene synthase (EC 4.2.3.100, Ov-TPS4) is an enzyme with systematic name (2E,6E))-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate bicyclogermacrene + diphosphate

The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor.

References

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  1. ^ Crocoll C, Asbach J, Novak J, Gershenzon J, Degenhardt J (August 2010). "Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis". Plant Molecular Biology. 73 (6): 587–603. doi:10.1007/s11103-010-9636-1. hdl:11858/00-001M-0000-0012-A513-2. PMID 20419468. S2CID 45230098.
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