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DIP2B

From Wikipedia, the free encyclopedia

DIP2B
Identifiers
AliasesDIP2B, disco interacting protein 2 homolog B
External IDsOMIM: 611379; MGI: 2145977; HomoloGene: 72227; GeneCards: DIP2B; OMA:DIP2B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020849
NM_173602

NM_001159361
NM_172819

RefSeq (protein)

NP_775873

NP_001152833
NP_766407
NP_001389830

Location (UCSC)Chr 12: 50.5 – 50.75 MbChr 15: 99.94 – 100.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DIP2 disco-interacting protein 2 homolog B (Drosophila) is a protein that in humans is encoded by the DIP2B gene.[5] A member of the disco-interacting protein homolog 2 protein family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence of these sites suggests that DIP2B may participate in DNA methylation. This gene is located near a folate-sensitive fragile site.[5][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000066084Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023026Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "DIP2 disco-interacting protein 2 homolog B (Drosophila)". Retrieved 2011-12-05.
  6. ^ Winnepenninckx B, Debacker K, Ramsay J, Smeets D, Smits A, FitzPatrick DR, et al. (February 2007). "CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1". American Journal of Human Genetics. 80 (2): 221–231. doi:10.1086/510800. PMC 1785358. PMID 17236128.

Further reading

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