Draft:SMCO2
Single-pass membrane and coiled-coil domain-containing protein 2 is a protein that is encoded in humans by the SMCO2 gene. A single-pass transmembrane protein is one that spans the membrane once, with one end of the protein exposed to the cytoplasm and the other end exposed to the outside of the cell.
Gene
[edit]Aliases
[edit]SMCO2 has 1 alias, C12orf70 (chromosome 12 open reading frame 70).
Location
[edit]SMCO2 is located on the plus strand of chromosome 12 (12p11.23) and spans 1234 base pairs.[1]
Expression
[edit]mRNA
[edit]Variants
[edit]There are 4 isoforms or variants of the SMCO2 gene. [2]
Regulation
[edit]Protein
[edit]General Properties
[edit]SMCO2 is 343 amino acids long with a molecular weight of ~40 kDa.[3]
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Composition
[edit]Domains and Motifs
[edit]Function
[edit]Clinical Significance
[edit]Mutations
[edit]Disease Associations
[edit]Evolution
[edit]Conservation
[edit]Homology
[edit]References
[edit]- ^ "C12orf70" NCBI mRNA. Retrieved 21 September 2024.
- ^ "C12orf70" NCBI gene. Retrieved 26 September 2024.
- ^ "C12orf70" NCBI Protein. Retrieved 21 September 2024.
- ^ "Pairwise Sequence Alignment" EMBOSS needle. Retrieved 28 September 2024.