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Guanosine-diphosphatase

From Wikipedia, the free encyclopedia
guanosine-diphosphatase
Identifiers
EC no.3.6.1.42
CAS no.98037-56-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

In enzymology, a guanosine-diphosphatase (EC 3.6.1.42) is an enzyme that catalyzes the chemical reaction

GDP + H2O GMP + phosphate

Thus, the two substrates of this enzyme are GDP and H2O, whereas its two products are GMP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is GDP phosphohydrolase. This enzyme is also called GDPase.

References

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  • Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins". J. Biol. Chem. 260 (14): 8306–11. PMID 2989286.