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Lactotriaosylceramide beta-1,4-galactosyltransferase

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Lactotriaosylceramide beta-1,4-galactosyltransferase
Identifiers
EC no.2.4.1.275
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Lactotriaosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.275, beta4Gal-T4, UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide beta-1,4-galactosyltransferase) is an enzyme with systematic name UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase.[1] This enzyme catalyses the following chemical reaction

UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

References

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  1. ^ Schwientek T, Almeida R, Levery SB, Holmes EH, Bennett E, Clausen H (November 1998). "Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis". The Journal of Biological Chemistry. 273 (45): 29331–40. doi:10.1074/jbc.273.45.29331. PMID 9792633.
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