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Lumpi-ProVacInd

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Lumpi-ProVacInd is a live attenuated vaccine for cattle, developed by the team of scientists led by Dr. Naveen Kumar, Principal Scientist at National Research Centre on Equines, Hisar, in collaboration with Indian Veterinary Research Institute, Izatnagar, both under the Indian Council of Agricultural Research[1][2] for prevention of Lumpy skin disease outbreak in India.[3][4] It was launched by Prime Minister Narendra Modi[5] and Agriculture Minister Narendra Singh Tomar.[6] Studies concluded that it is 100 percent effective for the prevention of the disease,[7] which complies with all government vaccine standards.[8] It was developed by using a local (Indian) LSD virus strain isolated by Dr Naveen in 2019 from outbreak in Ranchi, Jharkhand. The Neethling strain based LSD vaccines which is used in most part of the world has some side effects which include local inflammation at the site of injection, fever and a temporary reduction in milk yield in up to 15% animals. In contrast, the Ranchi strain based vaccine (Lumpi-ProVacInd) has no side effects; thereby it has high export potential-aiding to the make-in-India campaign. This vaccine has been commercialized and the technology has been transferred to at least 4 vaccine manufacturers in India which include, Biovet Pvt Ltd Bengaluru, Hester Biosciences, Ahmedabad, Indian Immunological Ltd Hyderabad and Institute of Veterinary Biological Products, Pune.

In 2024, the Central Drugs Standard Control Organization (CDSCO), Govt. of India, has approved the commercial production of Lumpi-ProVacInd by Biovet Pvt Ltd, Bengaluru.

Previously, in 2021, India authorized a goatpox (heterologous) vaccine against LSDV in cattle. However, later, experimental trials and several pieces of evidence from the field suggested that the goatpox vaccine (Uttarkashi strain) does not provide any significant protection against LSD in cattle.

References

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  1. ^ "How ICAR's new vaccine against Lumpy Skin Disease, the viral infection killing India's cattle, will work". The Indian Express. 2022-09-04. Retrieved 2022-10-09.
  2. ^ "Lumpy skin disease virus different from 2019 version". The Hindu. 2022-09-18. ISSN 0971-751X. Retrieved 2022-10-09.
  3. ^ "Patanjali working on finding solutions for Lumpy Skin Disease: Ramdev". The Economic Times. Retrieved 2022-10-09.
  4. ^ "Indigenous vaccine for lumpy skin disease ready, says Modi". The Tribune. Retrieved 2022-10-09.
  5. ^ "Big relief for livestock, Agriculture Minister Shri Tomar launches indigenous vaccine for Lumpy Skin disease". Press Information Bureau. Retrieved 2022-10-09.
  6. ^ "Agriculture Minister Launches 'Lumpi-ProVacInd,' an Indigenous Vaccine for Lumpy Skin Disease". Krishi Jagran. Retrieved 2022-10-09.
  7. ^ "Big relief for livestock, Agriculture Minister Shri Tomar launches indigenous vaccine for Lumpy Skin disease". Press Information Bureau. Retrieved 2022-10-09.
  8. ^ "Lumpy skin disease: Narendra Singh Tomar launches indigenous vaccine". The Indian Express. 2022-08-11. Retrieved 2022-10-09.