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MED11

From Wikipedia, the free encyclopedia
MED11
Identifiers
AliasesMED11, HSPC296, mediator complex subunit 11
External IDsOMIM: 612383; MGI: 1913422; HomoloGene: 32630; GeneCards: MED11; OMA:MED11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001305000
NM_001001683

NM_025397

RefSeq (protein)

NP_001001683
NP_001291929

NP_079673

Location (UCSC)Chr 17: 4.73 – 4.73 MbChr 11: 70.34 – 70.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mediator complex subunit 11 (Med11) is a protein that in humans is encoded by the MED11 gene.[5]

Function

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Med11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161920Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018923Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Mediator complex subunit 11".
  6. ^ Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, et al. (April 2003). "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". The Journal of Biological Chemistry. 278 (17). American Society for Biochemistry & Molecular Biology (ASBMB): 15123–7. doi:10.1074/jbc.c300054200. PMID 12584197.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.