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Nicotinate dehydrogenase (cytochrome)

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Nicotinate dehydrogenase (cytochrome)
Identifiers
EC no.1.17.2.1
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Nicotinate dehydrogenase (cytochrome) (EC 1.17.2.1, nicotinic acid hydroxylase, nicotinate hydroxylase) is an enzyme with systematic name nicotinate:cytochrome 6-oxidoreductase (hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

nicotinate + a ferricytochrome + H2O 6-hydroxynicotinate + a ferrocytochrome + 2 H+

This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases.

See also

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References

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  1. ^ Jiménez JI, Canales A, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E (August 2008). "Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440". Proceedings of the National Academy of Sciences of the United States of America. 105 (32): 11329–34. doi:10.1073/pnas.0802273105. PMC 2516282. PMID 18678916.
  2. ^ Yang Y, Yuan S, Chen T, Ma P, Shang G, Dai Y (July 2009). "Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440". Biodegradation. 20 (4): 541–9. doi:10.1007/s10532-008-9243-x. PMID 19118407. S2CID 23219659.
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