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RNF41

From Wikipedia, the free encyclopedia
RNF41
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRNF41, FLRF, NRDP1, SBBI03, ring finger protein 41
External IDsMGI: 1914838; HomoloGene: 4226; GeneCards: RNF41; OMA:RNF41 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001242826
NM_005785
NM_194358
NM_194359

NM_001164237
NM_026259

RefSeq (protein)

NP_001229755
NP_005776
NP_919339
NP_919340

NP_001157709
NP_080535

Location (UCSC)Chr 12: 56.2 – 56.22 MbChr 10: 128.25 – 128.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

E3 ubiquitin-protein ligase NRDP1 is an enzyme that in humans is encoded by the RNF41 gene.[5]

Function

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The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. The specific function of this protein has not yet been determined. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.[5]

Interactions

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RNF41 has been shown to interact with USP8.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181852Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025373Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: RNF41 ring finger protein 41".
  6. ^ Wu X, Yen L, Irwin L, Sweeney C, Carraway KL (September 2004). "Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8". Mol. Cell. Biol. 24 (17): 7748–57. doi:10.1128/MCB.24.17.7748-7757.2004. PMC 506982. PMID 15314180.

Further reading

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