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SULT4A1

From Wikipedia, the free encyclopedia
SULT4A1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSULT4A1, BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1, sulfotransferase family 4A member 1
External IDsOMIM: 608359; MGI: 1888971; HomoloGene: 49378; GeneCards: SULT4A1; OMA:SULT4A1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014351
NM_176874

NM_013873
NM_001356515

RefSeq (protein)

NP_055166

NP_038901
NP_001343444

Location (UCSC)Chr 22: 43.82 – 43.86 MbChr 15: 83.96 – 83.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sulfotransferase 4A1 is an enzyme that in humans is encoded by the SULT4A1 gene.[5][6]

This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130540Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018865Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Falany CN, Xie X, Wang J, Ferrer J, Falany JL (May 2000). "Molecular cloning and expression of novel sulphotransferase-like cDNAs from human and rat brain". Biochem J. 346. Pt 3 (3): 857–64. doi:10.1042/bj3460857. PMC 1220923. PMID 10698717.
  6. ^ a b "Entrez Gene: SULT4A1 sulfotransferase family 4A, member 1".

Further reading

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