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SpoIVB peptidase

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SpoIVB peptidase
Identifiers
EC no.3.4.21.116
CAS no.296241-18-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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SpoIVB peptidase (EC 3.4.21.116, sporulation factor IV B protease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB

This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.

References

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  1. ^ Wakeley PR, Dorazi R, Hoa NT, Bowyer JR, Cutting SM (June 2000). "Proteolysis of SpolVB is a critical determinant in signalling of Pro-sigmaK processing in Bacillus subtilis". Molecular Microbiology. 36 (6): 1336–48. doi:10.1046/j.1365-2958.2000.01946.x. PMID 10931284.
  2. ^ Hoa NT, Brannigan JA, Cutting SM (July 2001). "The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions". Journal of Bacteriology. 183 (14): 4364–73. doi:10.1128/jb.183.14.4364-4373.2001. PMC 95327. PMID 11418578.
  3. ^ Hoa NT, Brannigan JA, Cutting SM (January 2002). "The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases". Journal of Bacteriology. 184 (1): 191–9. doi:10.1128/jb.184.1.191-199.2002. PMC 134772. PMID 11741860.
  4. ^ Dong TC, Cutting SM (September 2003). "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis". Molecular Microbiology. 49 (5): 1425–34. doi:10.1046/j.1365-2958.2003.03651.x. PMID 12940997.
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