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Strombine dehydrogenase

From Wikipedia, the free encyclopedia
strombine dehydrogenase
Identifiers
EC no.1.5.1.22
CAS no.79393-84-3
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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In enzymology, a strombine dehydrogenase (EC 1.5.1.22) is an enzyme that catalyzes the chemical reaction

N-(carboxymethyl)-D-alanine + NAD+ + H2O glycine + pyruvate + NADH + H+

The 3 substrates of this enzyme are N-(carboxymethyl)-D-alanine, NAD+, and H2O, whereas its 4 products are glycine, pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in common use include strombine[N-(carboxymethyl)-D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase.

References

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  • Dando PR (1981). "Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L". Biochem. Soc. Trans. 9: 297–298.