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TLE3

From Wikipedia, the free encyclopedia
TLE3
Identifiers
AliasesTLE3, ESG, ESG3, GRG3, HsT18976, transducin like enhancer of split 3, TLE family member 3, transcriptional corepressor
External IDsOMIM: 600190; MGI: 104634; HomoloGene: 21059; GeneCards: TLE3; OMA:TLE3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083927
NM_001083928
NM_009389

RefSeq (protein)

NP_001077396
NP_001077397
NP_033415

Location (UCSC)Chr 15: 70.05 – 70.1 MbChr 9: 61.28 – 61.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transducin-like enhancer protein 3 is a protein that in humans is encoded by the TLE3 gene.[5][6]

TLE3 expression has been linked to higher survival rates for lung cancer patients.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140332Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032280Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Miyasaka H, Choudhury BK, Hou EW, Li SS (Aug 1993). "Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein". European Journal of Biochemistry. 216 (1): 343–52. doi:10.1111/j.1432-1033.1993.tb18151.x. PMID 8365415.
  6. ^ "Entrez Gene: TLE3 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)".
  7. ^ "Research update from the MCM team (February 2024)". World Community Grid. 16 February 2024. Retrieved 21 May 2024.

Further reading

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